8-in-1 Advanced KSM-66® Ashwagandha 600mg Root Extract Capsules
$29.50 USD
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8-in-1 Advanced KSM-66® Ashwagandha 600mg Root Extract Capsules
Chronic stress and elevated cortisol can disrupt focus, drain energy, and impair recovery.
Our 8-in-1 formula combines KSM-66® Ashwagandha with a science-informed combination of vitamins and botanical extracts to regulate cortisol levels, energy production and mood to sustain resilience throughout the day.
Verified potency. Clean-label. Science-informed. cGMP facility.
$29.50 USD
60 capsules | 30-days supply
Result*
Stress - Supports a more balanced cortisol response throughout the day.
Focus - Supports improved concentration, and mental clarity.
Energy - Helps to experience calm, steady energy without spikes or crashes.
Mood - Supports emotional stability and reduced irritability.
Recovery - Supports nervous system balance, helping muscles in the body relax.
Ingredients
- KSM-66® Ashwagandha 600mg
- Vitamin B12
- Vitamin B6
- Vitamin D3
- Maca Root Powder
- Panax Ginseng Root Powder
- L-Arginine
- Shatavari
- HPMC vegetable capsule
Verified Potency
Every formulation carries a Certificate of Analysis (COA) to verify product content and quality.
We use globally-sourced ingredients formulated in FDA-registered, GMP-certified facilities in the USA.
We formulate nutrient systems to support your connected biology.
Feel and function at your best - consistently.
SCIENCE-INFORMED FORMULATION
Why our Ashwagandha nutrient complex?
Stress is not only a psychological experience - it is a physiological process regulated by the hypothalamic–pituitary–adrenal (HPA) axis.
This system governs the release of cortisol, a hormone that plays a central role in energy metabolism, cognitive function, and recovery.
Chronic stress can disrupt this system, leading to imbalances in energy, mood, and overall physiological resilience.
Nutritional compounds such as adaptogens and micronutrients have been studied for their role in supporting the body’s stress-response systems and maintaining homeostasis.
The Quantity: 600 mg
The 600 mg daily amount of KSM-66 is the primary "gold-standard" dose used in the majority of clinical trials exploring this etract for its positive effect on Stress and Anxiety, Insomnia and Sleep, Memory and Cognition, Testosterone and Muscle Recovery.
Adaptogens and the Stress Response System
Adaptogens are a class of botanicals traditionally used to support the body’s ability to adapt to physical and mental stress.
Withania somnifera (Ashwagandha), particularly standardized extracts such as KSM-66®, has been widely studied for its interaction with the HPA axis and its role in supporting a balanced stress response.
Additional botanicals such as maca, ginseng, and shatavari have been investigated for their roles in supporting energy metabolism, endocrine balance, and overall vitality.
Together, these compounds are of interest for their complementary roles in supporting stress resilience and physiological equilibrium.
Mechanistic Insights from Research
Preclinical and human studies suggest that:
Ashwagandha may help support a balanced cortisol response and promote stress resilience
Adaptogenic compounds may influence the HPA axis, supporting the body’s ability to maintain homeostasis under stress
Certain botanicals may support mitochondrial function and cellular energy production
Micronutrients such as vitamins D3, B6, and B12 play roles in nervous system function and neurotransmitter synthesis
Amino acids such as L-arginine are involved in nitric oxide production, supporting circulation and nutrient delivery
These mechanisms are part of a broader network of biological processes involved in maintaining mental and physical performance under stress.
Dosage Considerations
Clinical studies investigating Ashwagandha extracts have commonly used standardized doses in the range of:
Ashwagandha (root extract): approximately 300–600 mg per day
Other adaptogens and supportive nutrients are studied across a range of intake levels depending on formulation and intended use.
There is currently no universally established optimal dosage for supporting stress resilience, and responses may vary depending on individual physiology and lifestyle factors.
ONGOING RESEARCH
Research into adaptogens and stress-response biology is ongoing.
Human clinical trials have shown promising results for Ashwagandha in supporting perceived stress and cortisol balance, though further research is needed to fully understand long-term effects and synergistic formulations.
Scientific Context
This information is intended to present current scientific understanding of stress-response physiology and the role of nutritional compounds. It is not intended to diagnose, treat, cure, or prevent any disease.
REFERENCES
Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults.
Indian J Psychol Med. 2012;34(3):255–262. doi:10.4103/0253-7176.106022
Lopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an Ashwagandha extract: a randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(37):e17186. doi:10.1097/MD.0000000000017186
Salve J, Pate S, Debnath K, Langade D. Adaptogenic and anxiolytic effects of Ashwagandha root extract in healthy adults: a double-blind, randomized, placebo-controlled clinical study. Cureus. 2019;11(12):e6466. doi:10.7759/cureus.6466
Panossian A, Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress—protective activity. Pharmaceuticals (Basel). 2010;3(1):188–224. doi:10.3390/ph3010188
Wankhede S, Langade D, Joshi K, Sinha SR, Bhattacharyya S. Examining the effect of Withania somnifera supplementation on muscle strength and recovery. J Int Soc Sports Nutr. 2015;12:43. doi:10.1186/s12970-015-0104-9
Smith AP, et al. Effects of maca supplementation on energy and mood: a systematic review. J Ethnopharmacol. 2018;220:148–156.
Reay JL, Kennedy DO, Scholey AB. Effects of Panax ginseng on cognitive performance and mood. J Psychopharmacol. 2010;24(4):547–557. doi:10.1177/0269881109106923
Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (Ashwagandha): a review. Altern Med Rev. 2000;5(4):334–346.
Benschop RJ, et al. Immune responses to stress and micronutrient interactions.
Brain Behav Immun. 2002;16(1):1–14. doi:10.1006/brbi.2001.0618
Moncada S, Higgs A. The L-arginine–nitric oxide pathway. N Engl J Med. 1993;329(27):2002–2012. doi:10.1056/NEJM199312303292706
OUR CAPSULE
Redefining daily vitality
Synergistic Nutrient Formulation
More than an isolated nutrient. We encapsulate nutrient combinations to support your connected biological system.
Clean-label, Bioavailable
Our capsules are designed to release nutrients where they’re best absorbed, with a fast-dissolving shell for quicker nutrient availability and no synthetic fillers to get in the way.
Designed for Consistency
We use ingredient levels consistent with those commonly studied in nutritional research.
THE SCIENCE
Nutrient intake at the times that your body clock needs it.
Your body follows a 24-hour circadian rhythm that influences energy levels, alertness, and rest cycles.
By aligning precisely-formulated nutrient combinations with these natural cycles, our Resilience Reset™ system supports consistency in how you feel and function throughout the day.
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8-in-1 Advanced KSM-66® Ashwagandha 600mg Root Extract Capsules
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Resilience Reset 3-Step Protocol
One protocol aligned to your body clock for consistent balanced energy
REGENERATE
3-in-1 Regeneration NAD+ 500mg + Resveratrol + Quercetin Capsules
3-in-1 NAD+ Resveratrol Quercetin / Cellular Health • Foundational Vitality
REGULATE
8-in-1 Advanced KSM-66® Ashwagandha 600mg Root Extract Capsules
KSM-66 600 mg Ashwagandha Nutrient Complex / Balanced Energy
RESTORE
Pure Restoration 275mg Elemental Magnesium Glycinate Capsules
275 mg Pure Elemental Magnesium Glycinate / Relax • Sleep • Recover
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We offer a 90-day money-back guarantee. Try the protocol risk-free. Verified potency. Science-informed. Clean. Vegan.
FAQ
Our mission is intentional nutrition - science-informed, clean-label, bioavailable nutrient combinations aligned with your body’s natural biology and designed for consistency.
01. What is the Circadian Rhythm
The circadian rhythm isthe body’s internal 24-hour clock, regulating sleep-wake cycles, hormone release, metabolism, and body temperature. It acts as a "master clock" that synchronizes with environmental cues like light and darkness. It governs daily cycles of alertness, digestion, and restorative sleep, significantly impacting overall physical and mental well-being.
Disruption: Environmental disruptions—like shift work, jet lag, or screen light at night—can throw off this rhythm, causing fatigue, poor focus, and long-term health issues like obesity or mental health disorders.
02. How is your Resilience Reset system different to energy drinks or caffeine?
Nutrition timed to support the circadian rhythm (chrononutrition) works by aligning energy intake with the body’s natural metabolic peaks to improve long-term health, whereas caffeine and energy drinks provide temporary, artificial alertness that often disrupts these natural rhythms and leads to metabolic imbalances.
03. Why a 3-step protocol?
We schedule supplements designed to support the circadian rhythm at specific, scheduled times throughout the day according to your body's varying metabolic, hormonal, and digestive needs.
Aligning our supplements with your natural body clock ensures maximum nutrient absorption, reduces stomach discomfort, and provides the necessary cues for wakefulness in the morning or repair and sleep at night.
04. Who is this designed for?
Our supplements use clean ingredients to support most dietary requirements.
Anyone can benefit from nutrient supplementation aligned to the circadian rhythm to support daytime energy and overnight restoration.
05. Can I get this nutrition from food and water?
Our encapsulations contain the ingredient quantities commonly explored by scientists to be effective when taken consistently.
We provide a precise quantity of a nutrient combination as a constant - to support changing food intake and schedules, ensuring your system consistently receives the nutrients it needs without the calorific tax and digestive stress.
06. Can I still have my Matcha or coffee?
Yes, you can generally take supplements designed to support your circadian rhythm while also consuming caffeine (coffee or matcha), but timing is crucial. Caffeine acts as a stimulant that can interfere with the body's natural sleep-wake cycle, while many circadian supplements aim toimprove sleep quality or regulate that same cycle.
Taking them together without considering timing can lead to counterproductive effects, such as reduced absorption of supplements or heightened anxiety.
REFERENCES
https://www.sleepfoundation.org/nutrition/caffeine-and-sleep#:~:text=Can%20Caffeine%20Cause%20Insomnia?,restful%2C%20restorative%20night%20of%20sleep.
https://www.facebook.com/THEVITAMINSHOPPE/posts/yes-you-can-have-your-supplements-and-your-coffee-tooyou-just-need-to-know-how-t/1197360882435581/#:~:text=Yes%2C%20you%20can%20have%20your,%E2%98%95%EF%B8%8F
https://mytrime.com/blogs/news/coffee-or-tea-the-effect-of-caffeine-on-sleep-and-circadian-rhythm?srsltid=AfmBOopT1ctUDLDleu0Hxh3e7DwnVlqi3jpNvRZVQKOOXOAwEQrvPD9u#:~:text=Problems%20arise%20when%20the%20effect,B%20vitamins%20and%20vitamin%20C.
Xhttps://www.eatingwell.com/supplements-to-avoid-with-coffee-11783883#:~:text=3.,B%20Vitamins&text=%E2%80%9CAvoid%20taking%20supplements%20with%20coffee,down%20easier%20after%20a%20meal.%22
https://reviveatlmd.com/whats-less-likely-to-disrupt-your-sleep-coffee-or-matcha/#:~:text=What%20time%20you%20drink%20your,day%20essential%20for%20many%20people.
https://reviveatlmd.com/whats-less-likely-to-disrupt-your-sleep-coffee-or-matcha/#:~:text=What%20time%20you%20drink%20your,day%20essential%20for%20many%20people.
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RESILIENCE RESET
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